Input variables Patient age Gender Female Male Patient category NSND SD Continuance of risk habits following diagnosis Yes No Not applicable Previous malignancy Solid - Head and Neck Solid - Others Hematologic malignancy No malignancy Charlson comorbidity index (link to index 1) (link to index 2) Hypertension status Yes No Diabetes mellitus status Yes No Hyperlipidemia status Yes No Autoimmune disease status Yes No Viral hepatitis status Yes No Type of lesion Oral leukoplakia Oral lichenoid lesion Type of lichenoid lesion Reticular/Papular Erosive/Atrophic Plaque Not applicable Tongue involvement Yes No Buccal/labial mucosa involvement Yes No Retromolar area involvement Yes No Gingiva involvement Yes No Palate involvement Yes No Number of lesions 1 2 ≥3 Presence of ulcers or red form Yes No Presence of induration Yes No Treatment type Surgical intervention Pharmacological treatment No treatment Recurrence following surgical intervention No recurrence Recurrence Not applicable - No surgical intervention Number of recurrence Not applicable 1 2 3 >3 Oral epithelial dysplasia - diagnostic biopsy No dysplasia Mild dysplasia Moderate dysplasia Severe dysplasia Unknown - Patient refused biopsy Oral epithelial dysplasia - follow-up biopsy No dysplasia/No follow-up Mild dysplasia Moderate dysplasia Severe dysplasia Unknown - Patient refused biopsy during follow-up Select Model Random forest with class weights Gradient boosting with ADASYN resampling Predict Clear